random thoughts to oil the mind

Tag: Biology Page 1 of 2

Hubris

One of the key ways we know how genes work is to look at what happens when they go wrong. We do this deliberately in experimental animals, precisely or randomly disrupting genes to see what happens. For obvious reasons, we don’t do that in people, but the equivalent is to study the genetics of disease and disorders.

A Brief History of Everyone Who Ever Lived: The Stories in Our Genes by Adam Rutherford

I wonder how small a minority I belong to when I react allergically to such naval-gazing conceitedness as this (emphasis my own).

The Man Who Mistook His Wife’s Head for a Hat

What happens when we are no longer able to recognise objects, but there’s nothing wrong with our ability to see? When we lose our sense of self and no longer feel the body we’re in? When the concept of ‘leftness’ is severed from our reality?

Oliver Sacks describes cases involving all these issues and more in a classic survey of ‘losses’ and ‘excesses’ in the human brain. The patients are a fascinating array of characters each suffering from such unusual problems that the symptoms seem almost comical. The eponymous man who failed to identify his wife’s head suffered from a form of visual agnosia, leaving him incapable of identifying objects, although his visual acuity was not impaired. Another sufferer had lost all ability to form new memories, and indeed was stuck at some point in his past, incapable of progressing past that point.

In a similar vein to Phantoms in the Brain, these eye-opening cases teach us much about the inner workings of the brain, they also encourage reflection on what it really means to be human, how our sense of self and perception is far more illusory than we really feel comfortable believing, and how little we really understand about how our cranial chemical factories really work.

If there’s one major detraction from this book in my eyes, it’s probably the fact that it’s written in English. The neglect the language has been shown by science leaves it so singularly pathetic at describing medical issues that we’re left with a gobbledegook of foreign words, even where Sacks tries to make the subject digestible for the average reader. Proprioception, for example, is a fascinating concept, and one so familiar to all of us that it’s amazing we don’t instinctively expect it to belong to that elite club of five senses, yet you won’t find me slipping the word into casual conversation any day soon.

On a side note, his descriptions of aphasia rather reminded me of my own feelings when learning a foreign language; that severe headache caused when trying to ram an idea down a set of neural pathways far too small to accommodate it.

[Photo by Jens Kreuter on Unsplash]

The Blind Watchmaker

Blind WatchmakerWhat is it about the theory of evolution which makes it so difficult to comprehend? Why does it require a leap of faith for many people to understand? And why do they feel they need to believe in evolution in a way they never would with, say, gravity?

Having finally got around to reading The Blind Watchmaker this year, one remark really stuck in my mind, when Dawkins turned to describing the human experience in terms of units. The way we perceive the world around us is intrinsically bound to the way we encounter it. We consider time, for instance, within a fairly specific range. Once we go beyond that range, our natural, indeed evolutionary faculties are incapable of perceiving the world outside those bounds with any degree of accuracy. That’s not to say we hit a brick wall when we step beyond that range. We’re still perfectly capable of contemplating the meaning of extremely long or short timescales, for example. We can measure them, compare them, calculate them; we can analogise and use metaphors. But we are far from being able to really grok what they mean.

Take things on the shorter end of the scale. Seconds are easily counted. We’re capable of working out how long a particular journey will take us, able to estimate how much faster it will be if we’re travelling by bicycle or car. But break the second down and it soon stretches into the theoretical. The speeding bullet or the flash of lightning travel far faster than our perception allows. Sometimes we can physically sense the difference, such as when a crack of lightning reaches our eyes before our ears, but beyond that, these events exist beyond our realm of experience.

At the other end of the spectrum, most of us find it difficult to measure things even in years. When did we move house? Was it three years ago, or four? When was that holiday to Cyprus? Five years ago? Six? We usually find little memory tricks to work out the answer, supporting our assumptions with unrelated facts (‘it was the year Jane started going to school… the Olympics were on in Beijing…’) Or we end up relying on physical evidence to corroborate the facts.

Where Dawkins really hits the nail is in how we view chance. With average lifespans under 100 years, we think relatively little of crossing roads, driving cars, climbing ladders or changing light bulbs. Accidents happen, people injure themselves and even lose their lives doing such mundane activities every day. But that only ever happens to other people. The risks are small; so small that we’re willing to take them on a daily basis. Experience teaches us the difference between perceptible and theoretical risk, the difference between the overt perils of grabbing a hot pan without oven gloves and the insidious hazards of an unhealthy diet.

Yet what would happen if we were to have natural lifespans in the hundreds of thousands or even millions of years? Those relatively slim chances of being fatally injured while crossing the road would suddenly have an entirely different dimension, given the number of times you do this in a lifetime. All of those otherwise hidden dangers, the risks we acknowledge without really understanding them, would become as clear to us as those overt dangers, since most people would come a cropper before reaching the natural limits of their lifespans.

The point is that our ability to contemplate unlikely events soon passes from the sensible to senseless. We grasp the chances of tossing heads, the likelihood of a rainy day in July. But beyond a certain limit, even the little sliver of rational thought in our minds gives way to thoughtless instinct. That one in a million chance becomes indistinguishable from impossible. A typical argument used against the theory of evolution runs along the lines that scientists have been trying to recreate the origins of life in the laboratory for decades. All their best efforts have been for nought, ergo that theory cannot possibly be true. Dozens of scientists in dozens of laboratories having been trying for dozens of years to reproduce an event that happened (at least) once across billions of planets in billions of solar systems over billions of years.

The numbers are staggeringly large, making them indistinguishable from impossible. And if not downright impossible, at least so perishingly unlikely that only with blind faith could you believe it to be true?

[Photo by jesse orrico on Unsplash]

Interesting little book review on the Irish Times website about the role of Cromwell in the disappearance of wolves in Ireland. Kieran Hickey’s book (possibly entitled The Natural and Cultural History of Wolves in Ireland—the article makes no reference) seems to confirm the role of Cromwell’s appearance in Ireland with the hunting and eventual extinction of the Irish wolf. I’m not aware of any attempts to reintroduce wolves to Ireland, and as this post on the Blather points out, there were fears that no one had learned from history, when policies in recent years called to cull badger numbers in the hopes of combating bovine tuberculosis.

Phantoms in the Brain

Phantoms in the Brain

In Phantoms in the Brain, V. S. Ramachandran has attempted to emulate the forebears he cites in the Preface, who inspired him to write science that is both informative and interesting to the general reading public. In this he has certainly succeeded, his style is highly approachable, and the content not only comprises interesting titbits, but wholly thought-provoking suggestions and analyses. I picked up Phantoms in the Brain on the basis of a recommendation from a friend more involved in the scientific fold than I am, yet found the book to be readily accessible to these with even only a meagre understanding of the way our brains function.

The book is for the most part concerned with the fundamental inner workings of the brain revealed to us through curiously specific medical conditions, often brought about by severe physical traumas such as strokes. Some of the findings are, perhaps, fairly well known by now, yet I’ve no doubt that many will still be quite shocking to most readers. However, Ramachandran keeps the presentation of both old and new findings fresh, in his natural inquisitive approach to each individual problem. His curiosity and novel attitude in dealing with many of these strange rarities of medical science at times remind one of the naïve questioning of a young child, who by approaching problems from altogether unexpected angles can come up with profound thoughts and solutions that would not normally strike an adult.

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